CJC-1295: what it is and what the evidence says
A synthetic GHRH analog that stimulates the pituitary to release the body's own growth hormone and, by binding to albumin in the blood, keeps acting for several days. It preserves pulsatile secretion and raises IGF-1 in a sustained way.
Last reviewed: August 16, 2026 · How we verify this
The ground it plays on
Hormones work in axes: a signal from the brain tells a gland to release another hormone, and so on down the chain, with brakes that shut the process off. Intervening at one point has consequences both upstream and downstream. That is why this is the group where professional assessment stops being a recommendation and becomes essential.
What it is studied for
Body composition, recovery, GH signaling.
There is a distinction that almost always gets lost. A compound being studied for something is not the same as achieving it. And even where it works in a dish or in a mouse, that says little about whether it works in a person or whether the benefit is worth the risk. The section below therefore carries more weight than everything above it.
What the human evidence says
Two controlled studies in healthy adults (J Clin Endocrinol Metab, 2006) showed that it raises GH and IGF-1 in a sustained way, with a half-life close to one week, and that secretion remains pulsatile.
The limitation that matters most
What has been studied in people is hormonal markers over a few weeks. Trials that measure body composition, performance, sleep or long-term safety are still missing, because clinical development stopped in 2006.
Regulatory status
No agency has approved it as a medicine. In December 2024 the FDA's advisory committee voted against adding it to the list of substances for pharmacy compounding. In sport, WADA prohibits it at all times under section S2 (GHRH analogs).
Status can change and varies by country. Always verify the rules in force where you live before drawing conclusions.
Cautions and context
It acts on the growth hormone axis and the response depends on each person's profile; watch IGF-1, glucose, fluid retention, and a faster pulse or flushing after an injection. For anyone who competes, it is on the WADA list (section S2).
Have a professional assess it before you start and while you use it, especially with diabetes or prediabetes, a history of cancer, heart disease, pregnancy or breastfeeding.
What this page cannot give you
A reference page can take you this far. You know what CJC-1295 is and where its research stands, which already puts you ahead of most readers. Four questions remain that no encyclopedia can answer for you, because the answers depend on your own situation:
- What would you measure beforehand, so that later you could tell whether anything actually changed?
- What would you watch along the way, and how consistently?
- What would you ask a professional, and in how much detail, so you do not walk out with a textbook answer?
- What would make you stop?
That is what the course is for
PeptiXtreme is ${CIF.LECCIONES} lessons that hand out no numbers. Each one ends with your starting point, what to watch along the way, the specific questions you take to a professional and the signals that mean stop. It includes per-module exams, a Certificate of Completion with a verifiable certificate ID, a Progress Tracker to follow how you are doing, and a human advisor you can actually write to.
See the course → Or measure your judgment, freeReferences
Every entry links to its record on PubMed, the US National Library of Medicine database. Open them and check. We would rather have a reader who verifies than one who takes our word for it.
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adultshuman J Clin Endocrinol Metab · 2006 · PMID 16352683 →
- Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analoghuman J Clin Endocrinol Metab · 2006 · PMID 17018654 →
- Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mousepreclinical Am J Physiol Endocrinol Metab · 2006 · PMID 16822960 →
- Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potionsreview Subst Use Misuse · 2016 · PMID 26771670 →
- Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparationpreclinical Drug Test Anal · 2010 · PMID 21204297 →
- Advances in the detection of growth hormone releasing hormone synthetic analogsreview Drug Test Anal · 2021 · PMID 34665524 →
Was this page useful?
Research moves, and when something relevant changes we update the page. If you want to hear about it for CJC-1295 or any other compound, leave your email. The introductory guide comes with it. No spam, no list-selling; one click to unsubscribe.
Frequently asked questions
What is CJC-1295?
A synthetic GHRH analog that stimulates the pituitary to release the body's own growth hormone and, by binding to albumin in the blood, keeps acting for several days. It preserves pulsatile secretion and raises IGF-1 in a sustained way. It is studied within the area of hormonal/sexual.
Is there human evidence for CJC-1295?
Two controlled studies in healthy adults (J Clin Endocrinol Metab, 2006) showed that it raises GH and IGF-1 in a sustained way, with a half-life close to one week, and that secretion remains pulsatile.
Is it approved by any health agency?
No agency has approved it as a medicine. In December 2024 the FDA's advisory committee voted against adding it to the list of substances for pharmacy compounding. In sport, WADA prohibits it at all times under section S2 (GHRH analogs).
What is the dose of CJC-1295?
We do not publish dosages. This is not an oversight. No single figure works for everyone: the regimen depends on a person's medical history, on whatever medication they already take, and on the goal they are chasing, which is something a professional weighs with the case in front of them. What you can build is the ability to walk into that appointment knowing what to ask.
Where can I learn to evaluate this properly?
This page tells you what CJC-1295 is and what the evidence says. The PeptiXtreme course teaches the other half: what you would measure before considering anything, what you would watch, the specific questions you would take to a professional and when you would stop.